CR5
CR5 may refer to multiple concepts across different fields. The most widely recognized use in biology is as an informal shorthand for CCR5, a chemokine receptor on the surface of certain immune cells. CCR5 acts as a coreceptor that, in conjunction with CD4, enables entry of R5-tropic strains of HIV-1 into host cells. Its natural ligands include the chemokines CCL3 (MIP-1α), CCL4 (MIP-1β), and CCL5 (RANTES). Genetic variation in CCR5, most notably the CCR5-Δ32 deletion, can reduce surface expression of the receptor and confer partial resistance to infection by R5-tropic HIV-1, though susceptibility depends on viral strain and other factors. CCR5 has been a target for antiretroviral therapy, and CCR5 antagonists such as maraviroc are used to block viral entry.
Outside biology, CR5 can be used as a general designation in product names, catalog numbers, or route
If you meant a different CR5, please specify the domain (for example, medicine, transportation, technology), and