CLTC1

CLTC1, also known as chloride channel 1, is a protein-coding gene that plays a role in regulating chloride ion transport across cell membranes. This gene is part of the CLC family of chloride channels, which are critical for various physiological processes. The protein encoded by CLTC1 is believed to function as a voltage-gated chloride channel, meaning its opening and closing are influenced by changes in the electrical potential across the cell membrane.

Mutations in the CLTC1 gene have been associated with certain neurological disorders, although the precise mechanisms are still under investigation. Research suggests that disruptions in chloride transport mediated by CLTC1 could impact neuronal excitability and synaptic transmission. Studies have explored its involvement in conditions such as epilepsy and other channelopathies. Further research is ongoing to fully elucidate the functional significance of CLTC1 and its contribution to human health and disease. Understanding its role could pave the way for new therapeutic strategies targeting chloride channel dysfunction.