CKDMineralstoffwechselstörung

CKDMineralstof is a term that refers to mineral metabolism disorders often associated with Chronic Kidney Disease (CKD). In individuals with healthy kidneys, the organs play a crucial role in regulating mineral balance, including calcium, phosphorus, vitamin D, and parathyroid hormone (PTH). When kidney function declines, this delicate balance can be disrupted.

A common consequence of CKD is hyperphosphatemia, an elevated level of phosphorus in the blood. This occurs because the kidneys are unable to effectively excrete excess phosphorus. High phosphorus levels can lead to secondary hyperparathyroidism, where the parathyroid glands produce too much PTH. Elevated PTH, in turn, can cause calcium to be leached from bones, leading to bone disease and increased risk of fractures.

Another aspect of CKDMineralstof is abnormal vitamin D metabolism. Healthy kidneys convert inactive vitamin D into its active form, calcitriol, which is essential for calcium absorption and bone health. In CKD, this conversion is impaired, contributing to low calcium levels and further exacerbating bone problems.

The management of CKDMineralstof involves addressing these imbalances. This can include dietary modifications to reduce phosphorus intake, phosphate binders to prevent phosphorus absorption, and vitamin D supplementation. Medications to control PTH levels are also often prescribed. Monitoring blood levels of calcium, phosphorus, PTH, and vitamin D is essential for guiding treatment and preventing complications.