CAPN11

CAPN11, also known as calpain 11, is a protein-coding gene. This gene belongs to the calpain family, which are calcium-dependent cysteine proteases. These proteases are involved in a variety of cellular processes, including cell growth, differentiation, apoptosis, and signal transduction. The specific function of CAPN11 is not as well understood as some other members of the calpain family. However, research suggests it may play a role in regulating muscle development and function. Studies have indicated that CAPN11 is expressed in skeletal muscle tissue. Mutations in the CAPN11 gene have been linked to certain genetic disorders. For example, it has been associated with hereditary leukonychia, a condition characterized by white discoloration of the nails. Further research is ongoing to fully elucidate the precise physiological roles of CAPN11 and its involvement in disease pathogenesis. The protein product of CAPN11 is a large subunit that requires association with a small regulatory subunit for its proteolytic activity.