C1QL1

C1QL1, also known as Complement C1q like 1, is a protein-coding gene. This gene encodes a protein that is a member of the C1q family. The C1q family proteins are part of the larger collectin and pentraxin superfamilies. Members of the C1q family are involved in the innate immune system, playing a role in pathogen recognition and complement activation.

The C1q-like proteins, including C1QL1, share structural similarities with the C1qA, C1qB, and C1qC subunits of the first component of the classical complement pathway. However, their precise functions are still being investigated and appear to be distinct from classical complement activation in some contexts. C1QL1 has been implicated in various biological processes, including neural development and synaptic plasticity. Research suggests it may interact with other proteins to modulate neuronal signaling and function.

Mutations or altered expression of C1QL1 have been associated with certain neurological disorders, although the exact mechanisms are not fully understood. Further research is ongoing to elucidate the full spectrum of C1QL1's roles in both the immune system and the nervous system. Understanding its functions could lead to new therapeutic strategies for a range of conditions.