Atg19s
Atg19s refers to a group of proteins that play a crucial role in autophagy, a cellular process responsible for degrading and recycling damaged organelles and proteins. Specifically, Atg19s are involved in selective autophagy, a pathway that targets specific cargo for degradation. In yeast, Atg19 is a key component of the autophagic machinery, acting as a receptor that binds to specific cargo molecules and links them to the growing autophagosome membrane. This binding is mediated by an Atg8-family protein, which is conjugated to the cargo.
The Atg19 protein itself possesses a domain that interacts with Atg8 proteins, and another domain that recognizes