Aptameres

Aptamers are short, single-stranded DNA or RNA molecules that are capable of binding to specific targets with high affinity and specificity. They are typically selected through a process called Systematic Evolution of Ligands by EXponential enrichment (SELEX), which involves iterative rounds of selection, amplification, and purification. Aptamers can bind to a wide range of targets, including small molecules, proteins, and even whole cells. They have been used in various applications, such as biosensors, drug delivery, and therapeutic agents. Aptamers offer several advantages over traditional antibodies, including their small size, ease of production, and stability. However, their use is limited by their relatively low binding affinity compared to antibodies and the potential for off-target binding. Aptamers have been extensively studied and have shown promise in various fields, including medicine, biotechnology, and environmental science.