ApoCaM
ApoCaM is a short, intrinsically disordered protein found in the synaptic cleft of neurons. Its primary role is thought to be related to the regulation of synaptic transmission and plasticity. ApoCaM is characterized by its lack of stable three-dimensional structure under normal physiological conditions, which allows it to interact with a variety of binding partners.
The protein was first identified in studies investigating presynaptic and postsynaptic mechanisms. Its sequence is highly
The disordered nature of ApoCaM is crucial for its function. This flexibility allows it to bind to
Research into ApoCaM is ongoing, with efforts focused on elucidating its precise molecular mechanisms and its