Amidiiniryhmän

Amidiiniryhmän refers to the amidine functional group in Finnish chemistry terminology. An amidine is a functional group with the general structure R-C(=NR')NR''R''', where R, R', R'', and R''' are organic substituents. This group is characterized by a carbon atom double-bonded to one nitrogen atom and single-bonded to another nitrogen atom. Amidines can be considered derivatives of carboxylic acids where the hydroxyl group (-OH) is replaced by an amino group (-NR2).

The basicity of amidines is a notable property. The delocalization of the positive charge within the amidinium ion, formed by protonation of the imine nitrogen, makes amidines stronger bases than amines. This enhanced basicity is due to resonance stabilization.

Amidines play important roles in organic chemistry and biochemistry. They are found in various biologically active molecules and pharmaceuticals. For instance, the guanidine group, a related functional group, is present in the amino acid arginine. Synthetic applications of amidines include their use as ligands in coordination chemistry and as building blocks in the synthesis of heterocyclic compounds. The reactivity of the amidine group allows for various chemical transformations, making them versatile intermediates in organic synthesis.