APH3II

APH3II is a protein found in *Arabidopsis thaliana*, a small flowering plant. It belongs to the aminophospholipid translocase family, often referred to as "flippases." These enzymes are crucial for maintaining the asymmetry of the cell membrane. Specifically, APH3II plays a role in the rapid, ATP-dependent transport of specific aminophospholipids, such as phosphatidylserine and phosphatidylethanolamine, from the outer leaflet of the plasma membrane to the inner leaflet. This movement is essential for various cellular processes, including signal transduction, membrane trafficking, and programmed cell death.

The gene encoding APH3II is *At4g11810*. Research has indicated that APH3II is likely involved in the regulation of phosphatidylserine distribution, which has downstream effects on the plant's response to environmental stresses. While its exact functions are still under investigation, studies suggest it may contribute to stress tolerance by modulating membrane composition and signaling pathways. Its presence and activity are important for normal plant growth and development.