ACTHstimulációs

ACTH stimulus or ACTH stimulation test is a medical diagnostic procedure used to evaluate the function of the adrenal glands, specifically their ability to produce cortisol. Adrenocorticotropic hormone (ACTH) is a hormone produced by the pituitary gland that stimulates the adrenal cortex to release cortisol. This test measures the cortisol response after administering a synthetic form of ACTH, cosyntropin.

The test is typically performed by first drawing a baseline blood sample to measure the current cortisol level. Then, synthetic ACTH is injected intravenously or intramuscularly. Subsequent blood samples are drawn at specific intervals, usually 30 and 60 minutes after the injection, to measure the rise in cortisol levels. A healthy adrenal gland will respond to the ACTH stimulation by significantly increasing cortisol production.

Abnormal results can indicate adrenal insufficiency, also known as Addison's disease, where the adrenal glands do not produce enough cortisol. It can also help differentiate between primary adrenal insufficiency (problem with the adrenal glands themselves) and secondary adrenal insufficiency (problem with the pituitary gland's ACTH production). Other conditions affecting the adrenal glands or pituitary gland may also be investigated using this test. The procedure is generally safe, with potential side effects being rare and mild, such as temporary discomfort at the injection site.