ACTHcentral

ACTHcentral is a web-based, collaboratively edited resource focused on the adrenocorticotropic hormone (ACTH) and its role in physiology, pathology, and clinical management. It provides concise, evidence-based information for students, clinicians, researchers, and patients, drawing on peer-reviewed literature and clinical guidelines. The site covers ACTH biology and regulation, laboratory testing and interpretation of ACTH, cortisol, and related stimulation tests, and a range of ACTH-related disorders.

Disorders addressed include secondary adrenal insufficiency (ACTH deficiency), ACTH-dependent Cushing's syndrome (Cushing disease and ectopic ACTH syndrome), and Nelson's syndrome, along with diagnostic challenges and differential diagnosis. Treatment topics span surgical, radiotherapeutic, medical, and endocrine replacement options, as well as management of comorbidities and follow-up care. Imaging, laboratory references, and patient education materials are provided to support understanding and decision-making.

Editorial and reliability: Articles are authored and reviewed by medical and scientific contributors, with citations linked to primary sources. The platform uses version history and discussion pages to track changes and resolve disputes. A clear disclaimer states that ACTHcentral is informational and not a substitute for professional medical advice. The content is regularly updated to reflect current evidence and guidelines.

Community and accessibility: The resource encourages contributions from clinicians, researchers, and patient advocates, subject to editorial oversight. It aims for neutral, accessible language and standardized terminology to support diverse readers. As a non-profit or independent project, ACTHcentral seeks to facilitate knowledge sharing while maintaining quality control.