3HT

3HT, also known as 3-hydroxytyramine, is a trace amine and a metabolite of the neurotransmitter dopamine. It is synthesized from dopamine by the enzyme monoamine oxidase (MAO) and further metabolized by catechol-O-methyltransferase (COMT). While dopamine is a major player in the central nervous system, 3HT is found in lower concentrations and its specific physiological roles are still a subject of ongoing research. Studies suggest that 3HT may be involved in regulating dopaminergic pathways and could potentially influence mood and behavior. It has also been investigated for its potential as a biomarker for certain neurological conditions, though its diagnostic utility is not yet established. 3HT is present in various tissues, including the brain, kidneys, and adrenal glands. Its presence and metabolism are influenced by factors such as diet and the activity of specific enzymes. Further research is needed to fully elucidate the functions and clinical significance of 3HT.