222kDa

222kDa is a protein that plays a significant role in various biological processes, particularly in the immune system. It is a member of the C-type lectin family, which includes proteins that recognize carbohydrate structures on the surface of cells. The protein is encoded by the 222kDa gene, which is located on chromosome 19 in humans. The gene is approximately 10 kilobases in length and contains five exons.

222kDa is expressed in a wide range of tissues, including the liver, spleen, and lymph nodes. It is involved in the recognition and clearance of pathogens, such as bacteria and viruses, by binding to carbohydrate structures on their surface. This binding triggers the activation of the complement system, a group of proteins that work together to destroy pathogens.

In addition to its role in the immune system, 222kDa has been implicated in other biological processes, such as cell adhesion and migration. It has also been studied for its potential role in various diseases, including cancer and autoimmune disorders. However, the exact mechanisms by which 222kDa contributes to these diseases are not yet fully understood.

The protein is a homodimer, consisting of two identical subunits, each with a molecular weight of approximately 111 kDa. It has a characteristic C-type lectin domain, which is responsible for its carbohydrate-binding activity. The protein also contains a collagen-like domain, which is involved in its interaction with other proteins and cells.

Overall, 222kDa is a multifunctional protein that plays a crucial role in the immune system and other biological processes. Its study has the potential to provide new insights into the mechanisms of immune function and disease.