1REL

1REL, also known as the gene for relaxin-like peptide 1, is a human gene that encodes a secreted peptide hormone. This hormone belongs to the relaxin-like peptide family, which are structurally related to insulin. The gene is located on chromosome 1, specifically at position 1q23.3. The protein produced by 1REL is thought to play a role in various physiological processes, although its exact functions are still being investigated.

Research has indicated potential involvement of 1REL in cardiovascular regulation, reproductive functions, and bone metabolism. It is expressed in a variety of tissues, including the heart, kidneys, and reproductive organs. Studies have explored its potential therapeutic applications in conditions such as heart failure and fibrosis, due to its vasodilatory and anti-fibrotic properties observed in preclinical models. Further research is ongoing to fully elucidate the biological roles and clinical significance of 1REL and its peptide product.