10×SDk

10xSDK is a software development kit designed to facilitate the integration of 10x Genomics single-cell and spatial genomics technologies into various research workflows. It provides a set of tools and libraries that enable researchers to access, analyze, and visualize data generated by 10x Genomics instruments. The SDK is primarily intended for bioinformaticians and computational biologists who wish to build custom analysis pipelines or integrate 10x data with existing computational frameworks.

The core functionality of 10xSDK includes reading and processing data files such as FASTQ, BAM, and VCF. It offers functionalities for tasks like demultiplexing, alignment, and variant calling, often leveraging pre-existing well-established bioinformatics tools. Furthermore, 10xSDK supports the analysis of specific 10x Genomics assay types, including Single Cell Gene Expression, Single Cell ATAC, and Spatial Transcriptomics. This often involves handling unique data formats and performing assay-specific data processing steps.

Users can employ 10xSDK to extract gene expression counts, identify cell populations, analyze genomic variations, and investigate spatial patterns of gene activity. The SDK's modular design allows for flexibility, enabling users to select and use specific components as needed for their particular research questions. While 10x Genomics provides its own set of analysis software, 10xSDK empowers researchers with greater control and customization over their data analysis, fostering deeper insights and enabling reproducible research practices.