zwitterionimuodon
Zwitterionimuodon, often referred to as the zwitterionic form, is a neutral molecule that contains both positive and negative formal charges. This phenomenon is particularly important in the study of amino acids, which are the building blocks of proteins. At a neutral pH, the carboxyl group of an amino acid loses a proton (H+) and becomes negatively charged (-COO-), while the amino group gains a proton and becomes positively charged (-NH3+). The molecule as a whole is electrically neutral because the positive and negative charges balance each other. This zwitterionic state is the predominant form of amino acids in aqueous solutions near physiological pH. The existence of zwitterions influences their physical properties, such as solubility and melting point, and is crucial for their biological functions, including their ability to act as buffers and participate in chemical reactions. The specific pH at which a molecule exists predominantly as a zwitterion is known as its isoelectric point (pI). At pH values below the pI, the molecule will carry a net positive charge, and at pH values above the pI, it will carry a net negative charge. This charge behavior is fundamental to techniques like electrophoresis, which separates molecules based on their charge and size.