tspC

tspC is a gene found in *Escherichia coli* and other bacteria. It encodes a protein that is part of the flagellar motor, a complex molecular machine responsible for bacterial motility. Specifically, the tspC gene product is a component of the stator, which is a protein complex that spans the cell envelope and translates the rotation of the motor's rotor into torque. This torque is what propels the bacterium through its environment.

The tspC gene is located within the *fliC-filG* operon, a cluster of genes involved in flagellar assembly and function. The protein encoded by tspC is thought to interact with other stator proteins, such as FliF and MotA, to form a functional proton channel. This channel allows protons to flow across the inner membrane, providing the energy required for the flagellar motor to rotate. Mutations in the tspC gene can lead to defects in flagellar assembly or function, resulting in reduced or absent motility. Understanding the role of tspC is crucial for deciphering the intricate mechanisms of bacterial locomotion and may offer insights into potential targets for antimicrobial agents.

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