thiopuriinilääkkeitä
Thiopurine medications are a class of immunosuppressive drugs used primarily in the treatment of autoimmune diseases, particularly rheumatoid arthritis and inflammatory bowel disease. They work by inhibiting the production of purines, which are essential components of DNA and RNA, thereby slowing down the proliferation of immune cells. Thiopurine medications include azathioprine and mercaptopurine, which are prodrugs that are metabolized in the liver to form active metabolites, 6-thioguanine and 6-mercaptopurine, respectively.
The primary use of thiopurine medications is in the treatment of rheumatoid arthritis, where they help to
Thiopurine medications are typically administered orally and have a slow onset of action, taking several weeks
Due to their immunosuppressive effects, thiopurine medications are not suitable for everyone and should be used