sequencespace
Sequence space is the set of all possible sequences formed from a given alphabet at a specified length. In biological contexts, the alphabet may be nucleotides (A, C, G, T or U) or amino acids, and the length corresponds to the number of positions in the sequence. The total number of sequences is k^L, where k is the alphabet size and L is the sequence length.
Formally, a sequence space can be viewed as the metric space (Sigma^L, d), where Sigma is the
In evolutionary and computational biology, sequence space is paired with a fitness landscape that assigns a
Applications include understanding protein evolution and design, RNA/DNA sequence optimization, and exploration of genotype–phenotype mappings. Limitations