rigetto

Rigetto is the Italian noun for rejection or refusal. It denotes the act of dismissing or denying something offered, such as a proposal, decision, or idea, and it can describe a negative response in social, professional, or administrative contexts. In medicine, rigetto also refers to the immune system's rejection of a transplanted organ or tissue.

From Latin rejicere, "to throw back," rigetto enters Italian with the base verb rigettare, meaning to reject. The noun is il rigetto; the plural is i rigetti. The participle and adjective forms include rigettato (rejected).

Usage: In everyday language, rigetto denotes the act of turning down something offered, such as a proposal or invitation: "Il direttore ha espresso rigetto verso la proposta." In legal language, a court might rigettare a claim, as in "Il tribunale ha rigettato la domanda" (The court rejected the petition).

Medical: In transplantation medicine, rigetto d'organo describes immune-mediated rejection of a transplanted organ. It can be hyperacute, acute, or chronic, and is managed with immunosuppression, monitoring, and sometimes re-transplantation. It is distinguished from non-immune failures such as graft dysfunction.

Beyond medicine and law, rigetto appears in literature and everyday discourse to characterize emotional or social rejection, such as a friendship or romantic rejection.