retinoidXreseptori
Retinoid X receptors, often abbreviated as RXRs, are a class of nuclear receptors that play a crucial role in gene regulation. They are members of the steroid hormone receptor superfamily. RXRs are unique in that they can form heterodimers with a variety of other nuclear receptors, including retinoid acid receptors (RARs), vitamin D receptors (VDRs), thyroid hormone receptors (TRs), and peroxisome proliferator-activated receptors (PPARs). These heterodimers bind to specific DNA sequences called response elements, which then modulate the transcription of target genes.
RXRs themselves can also form homodimers and bind to DNA. The ligands for RXRs are not fully
The physiological roles of RXRs are extensive and impact numerous biological processes. They are involved in