replikasjonsopprinnelsessted

Replikasjons-opprinnelsessted is a specific DNA sequence where the process of DNA replication begins. In both prokaryotes and eukaryotes, DNA replication is a semi-conservative process that starts at one or more predefined sites. For prokaryotes, such as bacteria, there is typically a single origin of replication. For example, in *Escherichia coli*, this origin is known as OriC. This sequence is rich in adenine and thymine bases, making it easier to unwind due to the weaker hydrogen bonds between these nucleotides compared to guanine and cytosine.

In eukaryotes, which have much larger and linear chromosomes, replication begins at multiple origins of replication. This allows for the rapid duplication of the entire genome. These origins are not randomly distributed but are often found in A-T rich regions and are recognized by specific initiator proteins. The unwinding of the DNA double helix at the replication origin creates a replication bubble, which expands bidirectionally as replication forks proceed along the DNA. The coordinated initiation and termination of replication at these sites are crucial for maintaining genomic integrity and ensuring accurate DNA inheritance.