pöörlemusringkonnad

Pöörlemusringkonnad, also known as rolling circles, are a type of DNA replication intermediate that arises when a circular DNA molecule is replicated bidirectionally. This structure is particularly associated with the replication of plasmids and viral genomes. During rolling circle replication, one strand of the circular DNA is nicked, and the intact strand serves as a template for the synthesis of a new complementary strand. As replication proceeds, the linear copy of the original circular DNA elongates, forming a long, single-stranded DNA molecule that is still attached to the circular template. This structure resembles a circle with a tail, hence the name "rolling circle." The newly synthesized DNA is then processed, either by being cleaved into individual circular molecules or by being used as a template for further replication. Pöörlemusringkonnad are important in the life cycles of certain viruses and can be used in molecular biology for the amplification of DNA. The efficiency and processivity of rolling circle replication make it a valuable tool in various biotechnological applications.