pxdet
Pxdet is a software tool designed for the detection and analysis of protein-protein interactions (PPIs) in mass spectrometry data. It is particularly useful in the field of proteomics, where understanding the interactions between proteins is crucial for comprehending cellular processes and functions. The tool operates by analyzing tandem mass spectra, which are generated when proteins are fragmented in a mass spectrometer. Pxdet identifies cross-linked peptides, which are fragments of proteins that have been covalently linked together due to a PPI. By detecting these cross-linked peptides, Pxdet can infer the presence of PPIs and provide information about the interacting proteins. The software is widely used in research laboratories and academic institutions for its accuracy and reliability in identifying PPIs. Pxdet's capabilities make it an essential tool for researchers studying protein interactions and their roles in various biological processes.