prothrombine
Prothrombin, also known as coagulation factor II, is a crucial protein in the blood clotting cascade. It is synthesized in the liver and circulates in the plasma in an inactive form. Its primary function is to be converted into thrombin, the enzyme that drives the formation of a stable fibrin clot. This conversion is a critical step in hemostasis, the process that stops bleeding.
The activation of prothrombin occurs through a series of enzymatic reactions. In the intrinsic and extrinsic
Once activated, thrombin plays a central role in coagulation. It converts soluble fibrinogen into insoluble fibrin