phosphothiolesters
Phosphothiolesters are a class of chemical compounds that contain a thiophosphate ester linkage. In these molecules, an oxygen atom in a typical phosphate ester is replaced by a sulfur atom. The general structure can be represented as R-S-P(=O)(OR')2 or R-S-P(=S)(OR')2, where R and R' are organic groups. The sulfur atom can be attached to the phosphorus atom in a P=S double bond (thionophosphate) or as a P-S single bond (thiophosphate). This sulfur substitution significantly alters the chemical and physical properties compared to their oxygen counterparts.
These compounds are of interest in various fields, particularly in biochemistry and medicinal chemistry. They can