peroksisomaalisii

Peroksisomaalisveti or peroksisomaalis-ulosykliset vetajärjestelmät are a type of cellular system found in eukaryotic cells. They are responsible for the breakdown of fatty acids and the detoxification of harmful substances. The term "peroksisomal" refers to the organelle in which these systems are located, the peroxisome.

Peroxisomal metabolic systems are involved in the degradation of very long chain fatty acids, branched chain fatty acids, and amino acids. They use a set of enzymes to break down these molecules into shorter chain forms that can be further processed by other cellular systems. In addition to their role in lipid metabolism, peroxisomal systems also carry out the oxidation of various organic compounds, including xanthine, hypoxanthine, and amino acids.

Mutations in genes involved in peroxisomal metabolism can lead to a range of disorders, known as peroxisomal biogenesis disorders (PBDs). These disorders are characterized by impaired lipid metabolism, leading to an accumulation of harmful byproducts in the cell and tissue damage. Examples of PBDs include Zellweger syndrome, neonatal adrenoleukodystrophy, and infantile Refsum disease.

Research has made progress in understanding the role of peroxisomal systems in cellular metabolism and their importance in human health. Studies have also shed light on the mechanisms underlying PBDs and the development of treatments for these conditions. Further research is ongoing to elucidate the intricacies of peroxisomal systems and their involvement in disease processes.