pegma

PEgMA, commonly written PEGMA, stands for poly(ethylene glycol) methyl ether methacrylate, a hydrophilic vinyl monomer used in radical polymerization to form water-swellable and biocompatible polymers.

The molecule combines a methacrylate functional group with a poly(ethylene glycol) methyl ether chain. The PEG side chain imparts hydrophilicity and tunable solubility, while the methacrylate group enables rapid, room-temperature polymerization with common radical initiators.

Synthesis and availability: PEGMA is typically prepared by esterification of poly(ethylene glycol) methyl ether with methacryloyl chloride or via transesterification from methacrylic anhydride; various chain lengths (n) are commercially available, allowing control of hydrophilicity and Tg in the resulting polymer.

Applications: It is widely used in hydrogel formulations, surface modification of biomaterials, coatings, contact lenses, and adhesives, where its hydrophilic character improves biocompatibility and moisture retention.

Safety and handling: As a reactive vinyl monomer, PEGMA can cause skin and eye irritation and should be handled with appropriate PPE and in well-ventilated areas. Polymerization inhibitors and storage under dry, cool conditions are typically recommended.