paralogsRAD51B

RAD51B is a human gene that encodes a protein belonging to the RAD51 family of proteins. These proteins are crucial components of the DNA repair machinery, particularly in homologous recombination. RAD51B, along with other RAD51 paralogs (RAD51C, RAD51D, XRCC2, and XRCC3), plays a role in maintaining genomic stability. The RAD51B protein is thought to function in the assembly of the RAD51 recombinosome, a complex that facilitates the search for and invasion of homologous DNA sequences. This process is essential for repairing double-strand breaks in DNA. Mutations or alterations in RAD51B have been associated with an increased risk of certain cancers, suggesting its involvement in tumor suppression. Research into RAD51B continues to explore its precise mechanisms of action in DNA repair and its implications for human health and disease.