oriCbinding
oriC binding refers to the process by which initiator proteins bind to a specific DNA sequence known as the origin of replication, or oriC. This binding event is a critical first step in DNA replication in many organisms, particularly bacteria. The oriC sequence is typically AT-rich and contains specific binding sites for the initiator protein, such as DnaA in *E. coli*.
Upon binding, the initiator protein undergoes a conformational change, often facilitated by ATP hydrolysis. This change