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Organotrophy is a metabolic strategy in which organisms obtain electrons from organic compounds. It is a subset of chemotrophy, distinguished from lithotrophy, where electrons are derived from inorganic substrates such as hydrogen, reduced minerals, or simple inorganic compounds. In organotrophy, energy can be harvested either by respiration, using external electron acceptors (for example oxygen, nitrate, or sulfate), or by fermentation, in which organic substrates serve as both electron donors and internal electron acceptors.
Organotrophs may be aerobic or anaerobic. In aerobic organotrophs, organic substrates are oxidized with an external
Organisms that exhibit organotrophy include many bacteria and fungi. Common examples are heterotrophic bacteria such as
Organotrophy is a fundamental concept in microbiology and biogeochemistry, helping to classify organisms by how they