natriumglukosecotransportere
Natriumglukosecotransporter (SGLTs) are a family of proteins that play a crucial role in the reabsorption of glucose in the kidneys and the absorption of glucose in the intestines. They are a type of secondary active transporter, meaning they use the electrochemical gradient of sodium ions to drive the transport of glucose against its concentration gradient.
There are several subtypes of SGLTs, with SGLT1 and SGLT2 being the most well-studied. SGLT1 is primarily
The function of SGLTs is essential for maintaining blood glucose homeostasis. By reabsorbing glucose, they prevent
Inhibition of SGLTs has emerged as a therapeutic strategy for managing type 2 diabetes. SGLT2 inhibitors, a