mucindomain
A mucin domain is a highly glycosylated region found in mucin glycoproteins. Mucins are large, secreted or membrane-bound proteins that are characterized by their abundant O-glycosylation. This extensive glycosylation is a hallmark of mucin domains and plays a crucial role in their function. The carbohydrate chains attached to mucins are typically rich in N-acetylgalactosamine (GalNAc) and are linked via serine or threonine residues. These glycosylation patterns can be highly variable and complex, contributing to the diversity of mucin functions.
The primary function of mucin domains is to confer specific biophysical properties to mucins. The heavily glycosylated
Mucin domains are also implicated in cell recognition, adhesion, and immune responses. The specific glycan structures