kortikosteroidia
Kortikosteroidia (corticosteroids) are a class of steroid hormones produced by the adrenal cortex and their synthetic analogues used as medicines. They are broadly categorized into glucocorticoids, which primarily affect metabolism and inflammation, and mineralocorticoids, which regulate electrolyte and fluid balance.
Glucocorticoids exert their effects by binding to the glucocorticoid receptor, altering gene expression to reduce production
Medically, corticosteroids substitute for deficient hormones (as in Addison disease) and treat a wide range of
Common adverse effects from systemic use include hyperglycemia, hypertension, weight gain, osteoporosis, myopathy, mood changes, and
Contraindications include active systemic fungal infections and certain hypersensitivity conditions. Interactions may occur with nonsteroidal anti-inflammatory