kolekystokiniinista

Kolekystokiniini, often abbreviated as CCK, is a peptide hormone produced primarily by cells in the duodenum and jejunum, the upper parts of the small intestine. It is also found in smaller amounts in the brain and other tissues. CCK plays a crucial role in digestion and satiety.

The primary function of CCK in the digestive system is to stimulate the gallbladder to contract, releasing bile into the small intestine. Bile aids in the digestion and absorption of fats. CCK also stimulates the pancreas to release digestive enzymes, which are essential for breaking down carbohydrates, proteins, and fats. Furthermore, it slows down gastric emptying, allowing more time for digestion and nutrient absorption in the small intestine.

Beyond its digestive roles, CCK acts as a satiety signal. When food, particularly fats and proteins, enters the small intestine, CCK is released, signaling to the brain that the body is full. This mechanism helps regulate food intake and prevents overeating. In the brain, CCK is believed to have various functions, including roles in anxiety, pain perception, and memory, although these are less understood than its peripheral effects. The release of CCK is triggered by the presence of fats, amino acids, and to a lesser extent, carbohydrates in the small intestine.