kerataansulfaattia

Kerataansulfaatti is a type of glycosaminoglycan (GAG) found in connective tissues. It is a linear polysaccharide composed of repeating disaccharide units. These units consist of an N-acetylglucosamine residue linked to a galactose-6-sulfate residue. Unlike other well-known GAGs like hyaluronic acid or chondroitin sulfate, keratan sulfate contains a sulfate group on the galactose moiety and an acetyl group on the glucosamine moiety. Its synthesis involves sulfation and polymerization of monosaccharide units. Keratan sulfate plays a role in maintaining the structural integrity and hydration of various tissues. It is particularly abundant in the cornea of the eye, where it contributes to the transparency and organization of stromal collagen fibrils. It is also found in cartilage, bone, and other connective tissues, albeit in smaller amounts. The functional properties of keratan sulfate are influenced by its degree of sulfation and its interaction with other matrix components, such as collagen. Research into keratan sulfate continues to explore its specific biological roles and potential therapeutic applications, particularly in areas related to vision and tissue repair.