integronide
Integronides are a class of natural products discovered in bacteria that possess antibiotic properties. They are characterized by a unique cyclic amide structure. The term "integronide" was coined to reflect their discovery and the presence of an integron-like gene cassette within their biosynthetic gene cluster in the producing organism. These compounds often exhibit activity against a range of bacterial pathogens, including Gram-positive and Gram-negative species.
The biosynthesis of integronides is a complex process involving a dedicated gene cluster. This cluster encodes
The discovery of integronides has generated interest in their potential as novel antibiotics, particularly in the