glycinerginic
Glycinerginic refers to a synapse or neuron that utilizes glycine as its primary neurotransmitter. Glycine is an amino acid that functions as both an excitatory and inhibitory neurotransmitter in the central nervous system. However, its inhibitory role is more prominent, particularly in the spinal cord and brainstem. When glycine binds to its receptors, it typically opens chloride channels, leading to hyperpolarization of the postsynaptic membrane and thus inhibiting neuronal firing.
The synthesis of glycine occurs through several pathways, including the conversion of serine by serine hydroxymethyltransferase.
Glycinerginic transmission plays crucial roles in various neuronal circuits. It is heavily involved in motor control,