glutámatpiruvát

Glutamatpiruvát, also known as alanine aminotransferase (ALT) or SGPT (serum glutamic pyruvic transaminase), is an enzyme predominantly found in the liver. Its primary function is to catalyze the transfer of an amino group from alanine to alpha-ketoglutarate, producing pyruvate and glutamate. This reaction is a key step in amino acid metabolism.

In medical diagnostics, serum ALT levels are a crucial indicator of liver health. Elevated levels in the blood typically suggest damage or inflammation of liver cells, such as in hepatitis, cirrhosis, or fatty liver disease. The enzyme is released into the bloodstream when liver cells are injured. ALT levels can also be affected by other factors, including certain medications, strenuous exercise, and muscle damage.

The measurement of ALT in serum is a routine part of liver function tests. While elevated ALT is a sensitive marker for liver injury, it is not specific to any particular liver disease. Therefore, it is usually interpreted in conjunction with other liver function tests and clinical findings to determine the underlying cause of the elevated levels.