fibrinról

Fibrin is a protein that plays a crucial role in blood clotting. It is formed from a precursor protein called fibrinogen, which is synthesized in the liver and circulates in the blood plasma. When a blood vessel is injured, a cascade of biochemical reactions is triggered, leading to the activation of thrombin. Thrombin then acts as an enzyme, converting soluble fibrinogen into insoluble fibrin monomers. These monomers spontaneously aggregate and polymerize to form a mesh-like network. This fibrin mesh traps blood cells and platelets, forming a clot that stops bleeding. The process of fibrin formation is a vital hemostatic mechanism, preventing excessive blood loss after injury. Once the wound has healed, the fibrin clot is broken down by another enzyme system involving plasmin. Fibrin is also involved in other biological processes beyond hemostasis, including wound healing and inflammation. Its presence can be detected and quantified in laboratory tests, providing insights into a patient's clotting status and potential bleeding or thrombotic disorders.