enzymetriggered
Enzyme-triggered describes processes or systems that rely on enzymatic activity to initiate, amplify, or regulate a response. The concept spans biochemistry, pharmacology, and materials science, and encompasses both natural biological processes and synthetically engineered systems. In biological contexts, enzymes act as catalysts that convert substrates into products, remove protective groups, or modify structures to change function.
In engineered constructs, a substrate or material contains an enzyme-cleavable or enzyme-activatable moiety. When the target
Applications include medicine, diagnostics, and materials science. In medicine, enzyme-triggered prodrugs release the active drug preferentially
Challenges involve variability in enzyme expression among individuals or disease stages, potential off-target activation, stability of