endokondroinen

Endokondroinen refers to a process of bone formation that occurs within cartilage. This is a primary mechanism by which long bones, such as those in the arms and legs, develop. The process begins with a hyaline cartilage model that resembles the future bone. Blood vessels then invade this cartilage model, bringing with them osteoblasts, the cells responsible for bone formation. These osteoblasts lay down bone tissue on the remnants of the calcified cartilage, gradually replacing it. This ossification process starts in the diaphysis, or shaft, of the bone and progresses towards the epiphyses, or ends, of the bone. Eventually, secondary ossification centers appear in the epiphyses, leading to the complete ossification of the bone, except for the articular cartilage and the epiphyseal plate, which allows for longitudinal bone growth. Endokondroinen ossification is a complex and well-orchestrated biological process essential for skeletal development and growth in vertebrates. It is distinct from intramembranous ossification, another method of bone formation that occurs directly from mesenchymal tissue without a cartilage intermediate.