dofetylid

Dofetilide is a prescription medication used to treat certain types of irregular heartbeats, specifically atrial fibrillation and atrial flutter. It belongs to a class of drugs known as Class III antiarrhythmics. Dofetilide works by affecting the electrical activity of the heart, helping to restore a normal heart rhythm and maintain it. It is typically administered orally and is available in capsule form.

Before starting dofetilide, patients usually undergo a period of hospitalization for monitoring. This is crucial because the drug can prolong the QT interval, a measure of the time it takes for the heart's ventricles to repolarize after a heartbeat. This prolongation can increase the risk of a potentially fatal heart rhythm disorder called Torsades de Pointes. The dosage of dofetilide is carefully adjusted based on individual patient factors, including kidney function, as the drug is primarily cleared by the kidneys.

Dofetilide is not suitable for everyone. It is contraindicated in patients with a history of QT interval prolongation or certain other heart conditions. Common side effects can include headache, dizziness, nausea, and chest pain. It is essential for patients to take dofetilide exactly as prescribed and to report any new or worsening symptoms to their healthcare provider immediately. Regular medical supervision is necessary during treatment.