derivatizersreagents
Derivatizing reagents are chemical compounds used in analytical chemistry to modify analytes—typically small molecules or ions—into more detectable or quantifiable derivatives. These reagents facilitate the analysis of compounds that are difficult to measure directly due to low sensitivity, lack of chromophore or fluorophore groups, or poor volatility. By reacting with target analytes, derivatizing reagents introduce functional groups that enhance detection via techniques such as gas chromatography (GC), liquid chromatography (LC), or mass spectrometry (MS).
A common application of derivatization is in gas chromatography, where thermally labile or polar analytes are
Derivatizing reagents can also improve selectivity by introducing specific functional groups that interact differently with chromatographic
The choice of derivatizing reagent depends on the analyte’s chemical properties, the detection method employed, and