cisplatinin

Cisplatin is a chemotherapy drug used to treat various types of cancer, including testicular, ovarian, bladder, lung, and head and neck cancers. It is also used in combination with other drugs to treat certain types of lymphoma and germ cell tumors. Cisplatin works by damaging the DNA of cancer cells, preventing them from dividing and growing. It is administered intravenously and has a short half-life, requiring frequent administration. Common side effects include nausea, vomiting, and kidney damage. Cisplatin is generally well-tolerated, but its use is limited by its toxic side effects and the development of resistance in cancer cells. The drug was first synthesized in 1965 and has since been a cornerstone in cancer chemotherapy.