biotransformaci
Biotransformation is the process by which living organisms modify chemical compounds through enzymatic reactions, typically to increase water solubility for excretion or to alter biological activity. It is a key aspect of metabolism in humans and other animals, but also occurs in microorganisms, plants, and environmental systems, influencing the fate, toxicity, and usefulness of many compounds.
Most biotransformations occur in two broad phases. Phase I reactions involve functionalization, such as oxidation, reduction,
Biotransformation has wide-ranging applications. In medicine, it determines drug clearance and potential interactions, influencing efficacy and
Genetic variation, age, diet, disease, and coadministered drugs can alter biotransformation rates, contributing to interindividual differences