beta2containing

Beta2containing is a nonstandard, contextual descriptor used in biochemistry and molecular biology to indicate that a molecule, complex, or sequence includes a beta-2 (β2) component. It is not part of a formal nomenclature, and its precise meaning depends on the source material. In practice, "beta2-containing" may denote a protein complex that includes a beta-2 subunit from any of several protein families, or a sequence that encodes a beta-2 subunit.

Common arenas include ion channels, receptors, and transporters that harbor beta-subunits such as the Na+/K+-ATPase beta-2 subunit (ATP1B2) or beta-subunits of voltage-gated calcium channels (CACNB2 is a beta-2 family member). G protein beta subunits (e.g., GNB2) are another example where "beta-2" forms part of a heterotrimeric complex.

In genomics and proteomics datasets, labeling an item as "beta2containing" typically highlights the presence of a β2-type subunit, which can influence localization, assembly, and regulatory properties. However, because the term spans multiple protein families, the exact function and physiological relevance vary by context. When encountered, researchers should consult the accompanying annotation to identify which β2-subunit is involved and what role it plays in the studied system.

See also: beta subunit, beta-2 subunit, Na+/K+-ATPase subunits, CACNB2, GNB2.