alfaactinin

Alfaactinin is a protein that belongs to the actinin family, which are involved in the regulation of actin filament dynamics. It is primarily expressed in smooth muscle cells and plays a crucial role in the regulation of smooth muscle contraction and relaxation. Alfaactinin interacts with actin and other proteins to form a complex that stabilizes actin filaments, thereby influencing muscle tone and contractility. Mutations in the alfaactinin gene have been associated with certain forms of hypertension and vascular smooth muscle dysfunction. The protein is also involved in the regulation of cell adhesion and migration, which are important processes in tissue repair and development. Alfaactinin is a target for various therapeutic interventions aimed at treating vascular diseases and other conditions associated with smooth muscle dysfunction.