YTHDC2

YTHDC2, also known as YTH domain containing 2, is a protein that plays a role in the regulation of gene expression. It belongs to the YTH domain protein family, which are known to bind to N6-methyladenosine (m6A) modified RNA. m6A is a prevalent internal modification in eukaryotic messenger RNAs and is involved in various RNA processing and regulatory events. YTHDC2 specifically recognizes and binds to m6A-modified RNA, influencing its fate.

The precise functions of YTHDC2 are still under investigation, but studies suggest it is involved in processes such as RNA splicing, translation, and stability. It has been implicated in cellular differentiation and development, particularly in germ cells. Research indicates that YTHDC2's activity can impact the expression of specific genes, thereby contributing to normal cellular functions and organismal development. Its dysregulation has been linked to certain diseases, highlighting its importance in maintaining cellular homeostasis. Further research is ongoing to fully elucidate the multifaceted roles of YTHDC2 in cellular biology and disease.